Metkinen Chemistry - reagents for DNA and RNA synthesis Metkinen Chemistry - Reagents for RNA and DNA synthesis.
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Alkyne Amidite, 5-terminal

Catalogue number: 501-13

Purity: > 95%

Molecular Weight: 409.50

Appearance: white crystalline solid

QC: 1H, 13C, 31P NMR

This amidite can be used for the preparation of oligonucleotides containing 5-terminal alkyne group. Resultant oligonucleotides are compatible to downstream modification by Click Chemistry (CuAAC) reaction.

Enhanced stability of secondary amidite group, together with solid form of this compound, facilitates handling. This makes this amidite ideal for routine use in post-synthetic modification protocols employing Click Chemistry.

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